Progeline Cream: Usage, Benefits, Side Effects, FAQs

Progeline Cream Guide

Human growth is an interesting mystery, the changes the human body undergoes as one age from an infant to an elderly person are genuinely fascinating.

The skin for example goes through a series of changes and then slowly begins to age when a person becomes elderly, the signs are visible as wrinkling and sagging skin begin to appear on a person’s body. Years before now, people might have accepted their fate and aged gracefully but these days with scientific research and development, there is a choice to slow down the aging process if you choose to and can afford the means involved.

The easiest and most popular way people get rid of skin aging changes is usually by undergoing plastic surgery. But that could be risky and complicated for some people, so the creation of anti-aging cream gives more people an opportunity to reverse or manage the skin sagging, wrinkling, dullness, and dehydration they experience during the aging process.

Progeline cream claims to be an impressive anti-aging cream according to the company that produces it, below is a complete guide that proves whether or not the anti-aging qualities of progeline are true.

What Is Progeline Cream?

Progeline is an exceptional biomimetic peptide that is believed to have anti-aging properties. It was invented by Lucas Meyer Cosmetics and is derived from Elafin. It contains a mixture of glycerin, water, and dextran, and trifluoroacetyl tripeptide (1).

Glycerin is a natural compound that is present naturally in plant and animal matter, it is also a skin treatment ingredient that traps moisture when in contact with the skin. Dextran is a polysaccharide found in artificial tears, while trifluoroacetyl tripeptide-2 inhibits all the previously mentioned ingredients and acts as an anti-aging peptide.

What Is A Peptide?

Since Progeline identifies as a peptide, it is important to understand what it is and how it functions. A peptide is a source of protein where two or more amino acids are combined. Peptides contain amino acids that are especially good for the skin.

The amino acids present in any peptide are usually fused as one by a chemical bond called a peptide bond. Peptides can contain as much as fifty amino acids in some cases depending on what they are being formulated to be used for.

Peptides are easier for the human body to absorb nutrients off (2) of because they are smaller than other sources of protein. They can penetrate the skin and intestines without the hassle and make contact with the bloodstream shortly.

According to their specific make-up of amino acids, peptides could both serve as a nutrient that improves the skin and possesses anti-aging properties or they could act as a nutrient that helps the body build its strength and muscle mass.

Progeline is a collagen peptide because of its anti-aging function in the body.

As a collagen peptide, it focuses on the human skin, with its main objective being to enhance overall skin health and slow down the aging process. Collagen peptides are known to remedy and reduce the appearance on wrinkles on the skin, it is also a vital protein supplement that may promote skin elasticity and hydration.

Progeline Cream Guide
Image: Envato Elements

These peptides may also boost the generation of melanin, this is meant to protect the skin from the effects of exposure to sunlight or simply curb sun damage as melanin strengthens the skin remarkably.

Collagen peptides (3) are also known to be present in several anti-aging products that are said to lower the appearance of wrinkles, aid in skin firming, and encourage increased blood flow. Collagen peptides may also serve as a remedy for preventing age-induced bone loss.

What Are The Benefits Of Progeline Cream For Skin?

Earlier identified as a collagen peptide, Progeline is known especially for being the body’s defense system against all forms of aging. As the skin naturally weakens, progeline is meant to serve as a strengthener that improves the overall appearance of the skin, retaining its finest qualities and rejecting the changes that are accompanied by the aging process.

However, are these claims true? It’s important that we determine that based on research and user experiences. Highlighted below are the benefits of Progeline creams to the skin;

1. Progeline Cream May Reduce Signs Of Aging In People

Reports have proven that after application, progeline cream does not smoothen wrinkles upon application, but since it is still being tested, people would like to believe that as a long term effect it and constant application it would eventually result in the smoothing of wrinkles in its bid to curb the effects of aging.

Other signs of aging such as skin sagging and volume loss are also meant to be reversed by the application of progeline cream to the skin. Instead, progeline has only been proven to smooth out fine lines on the skin as several moisturizers can easily do.

The Lucas Meyer Cosmetics Company states that the progeline cream is to serve the purpose of reducing progerin synthesis, inhibiting MMPs and Elatase, increasing syndecan, and contracts collagen. These are meant to slow down the aging process of the human body.

2. Progeline Is Known To Hydrate The Skin

One application of the progeline cream is sure to remarkably hydrate a person’s skin. Owing to the presence of glycerin and water in progeline cream the body is sure to get hydrated when it is used on the skin.

Glycerin is excellent for hydrating the skin because it draws moisture from the inner layer of the skin up to the epidermis to give the skin a healthy glow. It is the presence of glycerin that ensures the disappearance of fine lines on the skin when progeline cream is used.

Asides from skin hydration, the glycerin present in progeline cream makes for a soft and supple feel to the skin, and this is also why progeline cream is often likened to a moisturizer.

Progeline Cream Guide
Image: Envato Elements

What Are The Disadvantages Of Using Progeline Cream?

Progeline creams are still being researched by dermatologists and other doctors in related medical fields. This ongoing research may discourage persons to purchase the progeline cream because the long-term effects have not yet been determined.

It is however safe to say that progeline creams do not possess any ingredients that could cause harm to your skin. It is safe to purchase a progeline cream if you want to have an unbiased opinion on its originality based on the functions the Lucas Meyer Cosmetics Company outlines.

Purchasing a progeline cream that costs a lot of money while you are unsure it performs the functions it is said to, would only be a disadvantage when it does not turn out to indeed function as an anti-aging cream. If this is the case, you would have wasted good money being a means for research.

What Other Ingredients Help With Anti-Aging?

Since progeline has been proven as an unreliable treatment for anti-aging, below are some alternative ingredients in creams that firm the skin and eliminate wrinkles;

1. Retinoids

Retinoids are Vitamin A compounds such as retinol and retinoic acid. These particular ingredients have been instrumental in repairing skin damaged by the sun and reducing the appearance of fine lines and wrinkles on the skin.

2. Hydroxy Acid

Hydroxy Acids are a great anti-aging ingredient because of their ability to reduce dead skin, it is used to prepare and open up the skin to absorb other products properly. It also helps encourage the growth of smooth and even skin tone. These Alpha Hydroxy Acids include glycolic, citric, and lactic acids.

3. Vitamin C/Ascorbic Acid

Vitamin C in skin products are made use of because of their anti-oxidant qualities, this means it protects the skin from unstable oxygen molecules that destroy skin cells and result in wrinkles on the body. Vitamin C also protects the skin from sun damage as well as reduces fine lines and wrinkles on the skin.

Vitamin C serum
Vitamin C serum. Image: Envato Elements.

4. Niacinamide

A Niacinamide is an ingredient closely associated with Vitamin B-3 or Niacin, it also works as an antioxidant to decrease water loss in the skin and in some instances may boost skin elasticity to improve the overall appearance of the skin.

5. Tea Extracts

There are several skin DIY processes that are centered on using tea extracts to firm the skin. Apparently, green, black, and oolong tea possess solvents with anti-oxidant and anti-inflammatory abilities. With these present in a cream, it is likely to help in the prevention of wrinkles and fine lines.

Does Progeline Cream Really Work?

Unfortunately, there are not sufficient clinical data or research findings to prove that the functions mentioned by the company that produces progeline cream are indeed true. Within the short term of usage, people have complained and concluded that progeline creams do not work.

Progeline creams contain a higher concentration of dextran, glycerol, and water and a lesser concentration of peptide which should serve as the main ingredient for increasing the production of collagen in the body in order to fight the aging process in the human body.

The small amounts of peptide found in the progeline cream are gotten rid of by your body instead of absorbed to boost the release of collagen in your body. A progeline cream may only serve as a hydrating or moisturizing agent for the skin, not as an anti-aging product.

Progeline Creams Frequently Asked Questions

What Are The Ingredients In Progeline Cream?

The Progeline Cream contains four major ingredients which are water, glycerin, dextran, and a fluorinated peptide known as triflrifluoroacetyl tripeptide 2.

What Is Progerine Cream?

A Progerin cream is a bioengineered peptide formula gotten from Elafin for the skin by the Lucas Meyer Cosmetic Company, it is meant to be an effective cream that prevents saggy skin, the appearance of wrinkles hydrates the skin, and gives it volume. It is simply an anti-aging cream made from a mixture of water, glycerin, dextran, and triflrifluoroacetyl tripeptide 2.

Do Peptide Creams Really Work?

The studies that identify peptides as a means of collagen production to slow down the aging process make it seem like an effective treatment for wrinkles, saggy, dull, and dehydrated skin. Peptide creams have not been completely proven to correct the changes that accompany the big process but when applied religiously they are said to provide healthier skin.

How Long Does It Take For Peptides To Work?

Peptides can offer visible results within the first few weeks of being used, but to uncover their full potential or benefits, it would require a constant application for about three to six months for the peptides.


With the interest shown in skincare and beauty routines, it is no wonder that a cream such as progeline has so many unanswered questions. As an anti-aging cream progeline boasts of the ability to firm saggy skin, prevent wrinkles as a person ages, reduce the synthesis of progerin, and reduce volume loss.

These claims sound good and promising to a lot of people, the aging process is not particularly fun, and several persons would rather opt for a cream such as this instead of the surgeries that are commonly used to firm the skin and eliminate wrinkles.

Using a cream to slow down the again process sounds safer than undergoing surgical procedures so naturally, the thought of cream such as progeline would seem more appealing. However, judging from what is mentioned above based on the cream, it is still being researched and tested out to make certain that the mentioned benefits are achievable by applying the cream.

Judging from research that had been done, the progeline cream does not perform anti-aging functions. Instead, it acts as a moisturizer would by hydrating the skin and eliminating fine lines.

This would make one question the authenticity of peptides that are present in progeline cream, the simple explanation that suffices is that the concentration of peptides in the progeline cream is rather low in comparison to other ingredients.

The peptides ought to be the major ingredient because of their protein concentration that allows them to boost collagen production and in turn reverse the changes experienced during the aging process.

  1. Jenny Jin ( April, 2021 ), What Is Progeline Cream And Does It Really Work?
  2. Dr Hannah Sivak ( January 2020 ), What On Earth Is Progeline?
  3. Brooke Shunatona ( September 2021 ), Progeline Cream: Benefits And How To Use
  4. Future Derm ( December 2015 ), Do Peptides Really Work Or Not?
  5. Miami MD ( January 2021 ), What Is Progeline, And Why Is It Beneficial In Skin Care?
  6. Gundry MD ( January 2017 ), The Anti Aging Powers Of Progeline ( + How It Helps Fight Wrinkles! )
  7. Mayo Clinic ( 2020 ), Wrinkle Creams: Your Guide To Younger Skin

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